Furthermore, treatment of HER2+ breast cancer xenografts with the autophagy-inducing peptide Tat-Beclin 1 [70] inhibits tumor growth as efficiently as the tyrosine kinase inhibitor Lapatinib does, disrupts the Beclin 1-HER2 complex, and induces a unique transcriptional profile [68]. The gene discussed is BECN1; the disease is neoplasm.