Compared to control, stable transfectants of human neuroblastoma NB69 cell lines expressing Nme1 and mutant Nme1S120G form 2.8 and 3.6 times more colonies on soft agar, respectively, indicating that Nme1 aberrations provide neuroblastoma cells with additional in vitro colonization ability [65]. Here, NME1 is linked to neuroblastoma.