ITGA6 and cancer: Considering the up regulation of ITGA6 in cancer cells, notably under its ITGA6A form, our group has also evaluated this target in the stools of patients with colorectal lesions, based on the rationale that exfoliated cancer cells express higher levels of ITGA6 and are resistant to anchorage-dependent apoptosis, increasing the likelihood of detecting it in the stools (Figure 4).