A more extensive analysis revealed additional transcription factors that were significantly more highly expressed in the MYB-expressing ACC tumors including the genes encoding homeobox proteins SIX3 and PBX1; additional SOX proteins SOX6, SOX8, SOX9, SOX10, and SOX11; the forkhead domain protein FOXO3B; the ETS family protein ETV6; and the important tumor suppressor protein TP53 [7]. This evidence concerns the gene SOX6 and adrenal cortex carcinoma.