LEP and infection: There was also no significant difference in other outcomes including length of stay in the ICU or in the hospital, ventilation duration, ICU-associated infections and new renal replacement therapy between the two groups except ventilator associated pneumonia which was more common in patients with low leptin/ghrelin ratio group in comparison to the high leptin/ghrelin ratio group (14 (38.9%) vs. 8 (22.2%), p = 0.04).