TP53 and ovarian endometrioid carcinoma: Intriguingly, in both cases p53S185G substitution was found in tumors with known pathogenic TP53 mutations that alter the aminoacids H168 and K164 in the case of esophageal (COSP14113) [35] and W53 and W146 in the case of ovarian endometrioid carcinoma (COSP13878) [36].