RAB5A and infection: For example, recruitment of the small GTPase Rab5 to the vesicular surface during infection by Brucella abortus has been implicated in trafficking of the Brucella to a hospitable intracellular compartment; critically, Rab5 recruitment has been observed concomitant with invasion, during invagination of the clathrin-coated Brucella-containing vesicle [97].