The common upregulated genes in SCC and ADC included MAGEA9, KRT20, HOXD11, CST4, MAGEA1, MAGEA10, MAGEA4, FGF19, and CALM5. These genes are mainly associated with extracellular matrix and proliferation, promotion of tumorigenesis, and apoptotic processes [25,26,27]. This evidence concerns the gene CST4 and AIDS dementia complex.