The common upregulated genes in SCC and ADC included MAGEA9, KRT20, HOXD11, CST4, MAGEA1, MAGEA10, MAGEA4, FGF19, and CALM5. These genes are mainly associated with extracellular matrix and proliferation, promotion of tumorigenesis, and apoptotic processes [25,26,27]. The gene discussed is MAGEA4; the disease is AIDS dementia complex.