Additionally, it was found that HGK induced the expression of the microRNA (miRNA) miR-320a, which in turn inhibited the expression of the transcription factor FOXM1 and downstream FOXM1-regulated genes that are associated with epithelial–mesenchymal transition (EMT), thereby leading to the suppression of liver cancer cell growth and (potentially) metastasis. Here, MAP4K4 is linked to liver cancer.