PSME2 and colorectal cancer: Other members of the proteasomal protein of this network such as the PSMB7 was reported to be over-expressed in colorectal cancer [33], whilst PSME2 along with PSME3 were reported to be significantly enriched in several biological processes and pathways including cell adhesion, adherent junction organization, regulation of autophagy, cellular protein localization, the cell cycle, and the apoptosis pathway [34].