As shown in Figure 5, the number of mature blood vessels in the tumor of the control mice was higher (Figure 5D,F) compared to the number of blood vessel in the tumors from Ang1 KO mice (p-value < 0.0005) (Figure 5E,F), suggesting the presence of more immature vessels through vessel destabilization in the absence of Ang1. Here, ANGPT1 is linked to neoplasm.