APP and Anxiety: Although IH had no effect in WT mice, IH‐exposed APP/PS1 mice spent more time exploring the open arm (Figure 2c,d, F3, 34 = 9.632, p < .0001, one‐way ANOVA) and entered the open arm more frequently than their counterparts (Figure 2e, F3, 34 = 7.135, p < .0001, one‐way ANOVA), suggesting that IH attenuated anxiety‐related behaviors.