However, at 2.5 dpi with ECTV-dsRED, a significantly higher proportion of MHC-IIhi DCs were dsRED+ in the dLN of Cgas-/- mice compared to B6 indicating that Cgas-/- MHC-IIhi DCs are more susceptible to infection (Fig 4F). The gene discussed is CGAS; the disease is infection.