TP53 and hepatocellular carcinoma: The induction of TM4SF1 by KrasG12D was demonstrated in the present study, which was supported by two observations: (a) the mRNA level of TM4SF1 was elevated in the HCC mouse model driven by P53 loss and KrasG12D; (b) KrasG12D up‐regulated the mRNA level of TM4SF1 in L02 and 7404 cells.