Earlier studies have shown that SNXs are involved in the regulation of important signaling pathways associated with cancers, such as EGFR signaling (Kurten et al., 1996; Nishimura et al., 2012), Wnt signaling (Sun et al., 2016), TGF‐β signaling (Hao et al., 2011), and so on. The gene discussed is TGFB1; the disease is cancer.