CYP2W1 and neoplasm: Potent arylhydrocarbon receptor (AhR) ligands,4 benzothiazoles induce their own cytochrome P450‐mediated (CYP 1A1; CYP 2W1) biotransformation to electrophilic nitrenium species in sensitive tumour cells only.5, 6 These reactive species generate DNA adducts (N7‐guanine), which lead to lethal double DNA strand breaks7, 8—exclusively in cancer cells expressing cytosolic AhR and inducible CYP1A1 or CYP2W1.