It would be interesting to determine whether NCI‐N87 cells are responsive to GW 610, as CYP 2W1‐catalysed oxidation of GW 610 is 5‐fold more efficient that the CYP 1A1‐catalysed bioactivation.6 Structurally related GW 6106, 14, 24 demonstrated potent activity against mammary, ovarian carcinoma (demonstrating inducible CYP1A1) and also CRC cell lines expressing CYP2W1. The gene discussed is CYP1A1; the disease is ovarian carcinoma.