Viral infections are known to promote formation of another type of RNA granule, paraspeckles (Imamura et al., 2014), whereas spinal neurons in ALS, including ALS-FUS, are characterized by paraspeckle hyperassembly (An et al., 2019, Nishimoto et al., 2013, Shelkovnikova et al., 2018). Here, FUS is linked to viral infectious disease.