TSC2 and focal epilepsy: The mTOR genes including DEPDC5, TSC1 and TSC2 have been associated with focal epilepsy, as was the case in our study in which the mTOR genes had the highest yield (13/32), although the yield was relatively low in some previous studies (Lindy et al., 2018; Perucca et al., 2017; Carvill et al., 2013).