PRICKLE1 and myoclonic epilepsy: De novo heterozygous PRICKLE1 variants have been linked to congenital brain malformations or myoclonic epilepsies (Bassuk & Sherr, 2015; Todd & Bassuk, 2018), while two of three APEs with PRICKLE1 p.Ala541Ser variants in our study had non-lesional focal epilepsy and the other had acquired postencephalitic epilepsy.