FN1 and idiopathic pulmonary fibrosis: Further, mice receiving human-specific MAP3K19 siRNA from days 30–60 after IPF fibroblast injection had significantly less hydroxyproline (Fig. 2A), and a reduction in fibronectin and collagen 3 transcripts (Fig. 2B,C) compared with humanized C.B-17SCID/bg that received n/s RNA control RNA.