IL-10, having anti-inflammatory properties counter-regulates the cascade of pro-inflammatory cytokines and it has been reported to correlate with disease severity38 Remarkable, the results of the present study showed a significant impairment of IL-1Ra, IL-6, IL-8, IL-10, IL-12p40, TNF-α, MCP-1, and MIP-1b expression at 24 h, 48 h, and 72 h post-infection. The gene discussed is CCL4; the disease is infection.