RYR1 and myopathy: Two new models of recessive RYR1-related myopathies have recently been developed (Brennan et al., 2019; Elbaz et al., 2019) that aim to recapitulate the severe pediatric phenotypes of a subset of RYR1-related core myopathy patients (Amburgey et al., 2013; Jungbluth et al., 2011).