For instance, following genes were proven to be only associated with AD risk in Caucasian populations but not in East Asian populations: Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) [44, 45], Solute Carrier Family 24 Member 4 (SLC24A4) [46], NME/NM23 Family Member 8 (NME8) [47], GRB2 Associated Binding Protein 2 (GAB2) [48], Myocyte Enhancer Factor 2C (MEF2C) [49], Inositol Polyphosphate-5-Phosphatase D (INPP5D) [50], CLU [51], ABCA7, CD2AP, and EPHA1 [25], Fermitin Family Member 2 (FERMT2) [52]. The gene discussed is CLU; the disease is Alzheimer disease.