IL37 and primary biliary cholangitis: Firstly, biliary inflammation and injury in PBC are regulated by interleukin 12 (IL-12), interleukin 23 (IL-23) and interferon gamma (IFN-γ)32, so inflammatory cytokines might suppress the maturation of erythrocytes so that the newer and larger reticulocytes accelerate the entry into the peripheral blood circulation.