Representative tumor images of the staining of different scores are shown in Fig. S1A. Additionally, representative TMA images for nuclear, cytoplasmic, and negative staining of p27 are shown in Fig. S1B. The cytoplasmic p27 proportion scoring was not significantly associated with demographic variables, such as patient age, gender, race, or histologic subtypes of OS (Table S1). Here, CDKN1B is linked to neoplasm.