Previous studies have shown that p27 mislocalization occurs in multiple cancer types and the protein mislocalization correlates with poor prognoses (Ciaparrone et al., 1998; Fukumoto et al., 2004; Rosen et al., 2005), but the role of PAK1 in these p27‐mislocalized cancers is still elusive. The gene discussed is CDKN1B; the disease is cancer.