RYR2 and catecholaminergic polymorphic ventricular tachycardia: Recent experimental studies in transgenic mice carrying ryanodine receptor (RyR2) mutations, typically found in catecholaminergic polymorphic ventricular tachycardia (CPVT) patients, have demonstrated that the Ca‐dependent triggers of arrhythmia may originate in the Purkinje system (Cerrone et al., 2007; Kang et al., 2010; Willis et al., 2016).