JQ1 is a cell-permeable small molecule and can competitively bind to BRD4 fusion oncoproteins, such as BRD4-NUT, resulting in cancer cell differentiation and apoptosis.614 Similarly, I-BET762 is also a synthetic mimic of and competes with BRD4.615 Other compounds, such as MS417, OTX-015, RVX-208, OXFBD, I-BET151, PFI-1, MS436, and XD14, are also BET inhibitors and have been well illustrated in other published papers.616 We will focus on the associations between these compounds and cancers. Here, NUTM1 is linked to cancer.