KRAS and neoplasm: Furthermore, the overexpression of miR-202 was found to inhibit the Ras/MAPK pathway by targeting the KRas gene.36 A similar phenomenon has been observed with other miRNAs, including miRNA-48a-3p and miR-193a-3p.37,38 In Liang Ma’s study, the researchers found that miR-148a-3p inhibited the development and progression of NSCLC by reducing the expression of SOS (son of sevenless) via Ras/MAPK/Erk signaling.90 In addition, decreased expression of miR-193a-3p was found in the NSCLC tumor tissues and inhibited cell proliferation and progression.