To further investigate the expression of the four newly identified hypermethylated cervical cancer-specific markers in human CSCC specimens, we assessed the protein levels of GABRA2, ZNF257, SLC5A8, and RAB3C by immunohistochemistry (IHC) using tissue arrays containing 93 human CSCC samples and paired cancer-adjacent normal tissues. The gene discussed is ZNF257; the disease is cervical cancer.