The pathologic diagnosis at that time was invasive ductal carcinoma, stage IIA: tumor (T) 2, node (N) 0, metastasis (M) 0, lymphatic invasion (Ly) 0, venous invasion (V) 0, estrogen receptor (ER) (−), progesterone receptor (PgR) (−), human epidermal growth factor receptor 2 (HER2) (−). This evidence concerns the gene ESR1 and invasive ductal breast carcinoma.