Interestingly, it seemed that HOXC-AS1 affected MYC expression in GC through not only miR-590-3p-mediated manner but also another unknown pathway because the qRT-PCR revealed that miR-590-3p inhibitor only partly restored MYC level in GC cells transfected with shHOXC-AS1#1 (Fig. 5a). The gene discussed is MYC; the disease is gastric cancer.