CDH2 and gastric cancer: Similarly, depletion of HOXC-AS1 also apparently repressed epithelial-mesenchymal transition (EMT) in GC cells, as the level of epithelial marker E-cadherin was heightened while that of the mesenchymal markers N-cadherin and Vimentin lowered in the context of HOXC-AS1 suppression (Fig. 2g).