The cell cycle-related molecules CDK1 and CCNB1 are the most connected hub genes, and these genes have been reported to be potential diagnostic or prognostic markers in a variety of tumours, such as glioblastoma malignancies [9], hepatocellular carcinoma [10, 11] and non-muscle invasive bladder cancer [12]. Here, CDK1 is linked to hepatocellular carcinoma.