Compared to the VDR Cdx2 AC genotype, the VDR Cdx2 CC genotype was associated with increased levels of fasting insulin and HOMA-IR in women with PCOS, however, the associations were not statistically significant in multiple linear regression analyses (P = 0.081 and 0.085, respectively, Table 5). This evidence concerns the gene VDR and polycystic ovary syndrome.