XPO1 and malignant colon neoplasm: The anti-proliferative effect of XPO1 inhibitors were reported in different types of cancer cell lines such as pancreatic cells (Azmi et al., 2017), liver cells (Zheng et al., 2014), prostate cells (Gravina et al., 2015), and gastric cells (Subhash et al., 2018) as well as in colon cancer cell lines (Draetta et al., 2011; Niu et al., 2015).