XPO1 and neoplasm: Association of XPO1 overexpression with high tumor grade and advanced tumor stage (Noske et al., 2008; Shen et al., 2009) as well as with poor prognosis was noted in some tumor cancers such as gastric (Zhou et al., 2013), ovarian (Noske et al., 2008) and acute leukemia (Kojima et al., 2013), but little is known about such association between the XPO1 overexpression and clinicopathological characteristics in CRC.