The results of several studies reported that c-Myc is incriminated in pathogenesis of BC and suggested a significant association between overexpression of c-Myc protein and high tumor grade and advanced tumor stage (Mahdy et al., 2001; Watters et al., 2001; Watters et al., 2002; Zhao et al., 2015; Li et al., 2016). This evidence concerns the gene MYC and breast cancer.