MYC and metastatic malignant neoplasm in the lymph nodes: In our study, high c-Myc nuclear expression of the overall tumor was significantly associated with sarcomatoid variant, PNI, LVI, lymph node metastasis, distant metastasis and advanced stage grouping, while there was no significant association with gender, age, tumor diameter, divergent differentiation, bilharziasis, necrosis, pathological tumor stage (pT) and recurrence.