Tumour necrosis factor alpha (TNF-α) and numerous cytokines, such as interleukin 1 beta (IL-1β), 6 (IL-6) and 10 (IL-10), are associated with the activation of the cell cycle, leading to tumour progression and metastasis development (Eirón et al., 2012). The gene discussed is IL10; the disease is neoplasm.