TLR3 and colorectal carcinoma: To shed light on the potential role of the single nucleotide polymorphisms (SNPs) within the TLR3, CGAS, TMEM173, TBK1, and IKBKE genes, we genotyped a set of 11 potential regulatory SNPs in a case‐control study of 1424 CRC patients and 1114 healthy controls from the Czech Republic and evaluated their association with CRC risk.