In this study, we included only five members of the TLR3/cGAS‐STING‐IKKε‐TBK1 signaling cascade, which has recently been reported to be disturbed in CRC due to deregulated expression of the genes involved,19 in addition to nine IFN genes from our previous studies to evaluate their genetic interactions. This evidence concerns the gene TLR3 and colorectal carcinoma.