To this extent, we used surgically resected brain tissue from patients with drug‐resistant epilepsy due to FCD IIb or TSC and a mouse epilepsy model based on conditional Tsc1 deletion in glial fibrillary acidic protein (GFAP) expressing cells (Tsc1GFAP−/− mice) to investigate these interactions. Here, TSC1 is linked to tuberous sclerosis.