Adjusted for age, gender, diabetes mellitus, coronary artery disease, heart failure, stroke, systolic blood pressure (SBP) total cholesterol, diuretics, angiotensin-converting-enzyme inhibitor/angiotensin receptor blockers, estimated glomerular filtration rate (eGFR), serum albumin, hemoglobin, white blood cell (WBC). This evidence concerns the gene ACE and heart failure.