RUNX1 and acute myeloid leukemia: Finally, to investigate whether the dynamic H3K27ac regions between AML1-ETO expressing and normal differentiating iGranulocytes reflect differences observed between primary granulocytes and AML1-ETO expressing AMLs we examined the same H3K27ac increased and decreased peak regions in 7 mature neutrophils (http://dcc.blueprint-epigenome.eu/#/datasets/EGAD00001000930) and two t(8;21) positive primary AML patient samples (http://dcc.blueprint-epigenome.eu/#/datasets/EGAD00001001481; S00Y4YH1 and S013SSH1).