KLF4 and glycogen storage disease II: We next employed DeepNEU to generate the unsupervised aiPSC model of infantile onset POMPE disease (IOPD) by again turning on the transcription factors OCT3/4, KLF4, SOX2, cMYC plus MyoD1 in the presence of Doxycycline, but this time the GAA gene which makes the enzyme normally responsible for lysosomal conversion of glycogen to glucose was locked off.