Mutations in the murine IL-36RN gene have been associated with a psoriasiform dermatitis phenotype, whereas mice deficient in IL-36 or IL-36R were protected from imiquimod-induced psoriasiform dermatitis (Barton et al., 2000; Blumberg et al., 2007; Tortola et al., 2012). Here, IL1RL2 is linked to Psoriasiform dermatitis.