In a study from Thailand, Sripa et al. (2012b) investigated the relationship between plasma levels of IL-6 and the risk of developing advanced fibrosis and bile duct cancer due to chronic Opisthorchis infection and found 58 times higher IL-6 concentration in plasma of individuals with advanced fibrosis compared with age, sex, and nearest-neighbor matched controls. The gene discussed is IL6; the disease is bile duct cancer.