In addition, Fibroblast Growth Factor 2 (FGF2) is seen in most mesothelioma tissue specimens by immunohistochemistry (IHC) (33, 38, 39) and leads to proliferation of fibroblast cell lines in vitro and migration to the malignancy in xenograft models in SCID mice (33). The gene discussed is FGF2; the disease is mesothelioma.