Expression of the eight upregulated genes (YRDC, CCT6A, ACTG1, DDOST, UTP18, RRP12, NLE1, as well as RFT1) increased both in COAD and its subtypes compared with normal, while the expression of RHOQ decreased both in COAD and its subtypes. Here, RFT1 is linked to colon adenocarcinoma.