After reviewing the literature, we found that four upregulated genes comprising of TUBA1C (Li et al., 2017; Wang et al., 2017), ABCE1 (Hlavata et al., 2012; Tian et al., 2016), UBE2N (Kim et al., 2015; Dikshit et al., 2018), and NIFK (Pan et al., 2015; Lin et al., 2016) had been reported to function in tumor growth, proliferation, migration, metastasis, and prognosis. This evidence concerns the gene UBE2N and neoplasm.