High expressions of CCT6A, RRP12, and RHOQ promoted growth of COAD cell lines and were relative to poor prognosis, while high expressions of UTP18, DDOST, YRDC, ACTG1, RFT1, and NLE1 were relative to good prognosis, although they promoted growth of some COAD cells. The gene discussed is DDOST; the disease is colon adenocarcinoma.