Moreover, the latency time as well as the tumor load per animals was significantly lower in Ptch+/- mice [tumor-bearing mice after 18 weeks: 25% (3/8 mice); tumor load/mouse after 26 weeks: 1.373 +/- 0.532] compared to the controls [tumor-bearing mice after 18 weeks: 100% (5/5 mice); tumor load/mouse after 26 weeks: 4.2 +/- 1.158] (Figures 6A, B). The gene discussed is PTCH1; the disease is neoplasm.