In a novel mouse model of non-allergic asthma overexpression of the activator protein-1 (AP-1) subunit Fra2, caused airway inflammation with IL-13 overexpression, BAL eosinophilia, mucus hyperproduction, AHR, and peribronchial collagen deposition (Gungl et al., 2018). Here, JUN is linked to Increased total eosinophil count.