angustatus Besser (Acoraceae) (6 g), tuber of G. elata Blume (Orchidaceae) (10 g), rhizome of Polygonatum sibiricum Redouté (Asparagaceae) (10 g), and fruit of L. lucidum W.T.Aiton (Oleaceae) (10 g), which decreased Aβ and p-tau levels and increased acetylcholine and glutamic acid levels in the CA1 region of hippocampus in AD mice. The gene discussed is MAPT; the disease is Alzheimer disease.