PTGS2 and breast cancer: Other researchers reported that genistein suppressed inflammatory responses through inhibition of COX‐2, phosphorylated c-Jun N-terminal kinase (JNK), protein kinase R-like ER kinase, and pp38 and in vitro and in vivo studies MCF-7 breast cancer cell line and mammary glands of female rats, respectively, (Hwang et al., 2009).