Scanning electron microscopy (SEM) and thioflavin-T fluorescence assay have revealed: (i) that LPS and/or LPS-binding protein (LBP) have strong disruptive effects on the structural and biophysical organization of Aβ peptides and amyloidogenesis in Parkinson’s disease (Montagne et al., 2017; Pretorius et al., 2018); and (ii) that LPS strongly induces NF-kB signaling, inflammatory responses, neuroinflammation, the generation of Aβ42 peptides and amyloidogenesis in transgenic murine models of AD (Gu et al., 2018; Jeon et al., 2019; Sheppard et al., 2019). The gene discussed is LBP; the disease is Parkinson disease.