VEGFA and rheumatoid arthritis: Figure 4 demonstrates increased secretion of key angiogenic mediators, VEGFA, TSLP, Flt-1, and Tie-2, from untreated PsA SFC compared to RA SFC, yet other angiogenic mediators remain unchanged between the PsA SFC and RA SFC (Fig. 4; Additional file 2: Figure S2).