Figure 4 demonstrates increased secretion of key angiogenic mediators, VEGFA, TSLP, Flt-1, and Tie-2, from untreated PsA SFC compared to RA SFC, yet other angiogenic mediators remain unchanged between the PsA SFC and RA SFC (Fig. 4; Additional file 2: Figure S2). The gene discussed is FLT1; the disease is rheumatoid arthritis.